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Journal of diabetes metabolism and its complications, Blood test could predict diabetes years befor | EurekAlert!


    Email For pregnant women, gestational diabetes can be a troubling complication.

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    While GDM can often be controlled through proper diet, exercise and medication, early diagnosis and treatment are crucial for women hoping to manage their high blood sugar and prevent complications during their pregnancy. Therefore, women who develop GDM and do not have these common risk factors often remain undiagnosed until the second trimester — and a delay in diagnosis often means therapies for GDM are less effective.

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    If left untreated, GDM can increase the risk of jaundice, breathing issues and hypoglycemia in the newborn child. More extreme side effects of uncontrolled GDM include the risk of premature delivery, preeclampsia, and even the death of the child before or shortly after birth.

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    The researchers believed that measuring levels of s P RR — the soluble form of P RR found in the bloodstream — could help predict whether or not pregnant women eventually develop diabetes. Using the popular diagnostic enzyme-linked immunosorbent assay ELISA test, the team analyzed the blood of pregnant women during their first trimesters, measuring for their levels of s P RR.

    According to Ichihara, the increased levels of s P RR suggest that the mothers are experiencing slowed metabolisms, putting them at risk for GDM.

    Ichihara said the test could also come in handy for detecting other conditions, as recent studies have found a connection between elevated s P RR levels and the birth of larger babies and high blood pressure in late pregnancy.

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