Modeling long-term diabetes and related complications in rats

Diabetes mellitus latest research. People with pre-diabetes who drop substantial weight may ward off type 2 diabetes -- ScienceDaily

Tartalom

    Modeling long-term diabetes and related complications in rats J Pharmacol Toxicol Methods. Mar-Apr ; Epub Nov Gyömrői út Electronic address: erika.

    osin kezelés során a diabetes 4 es típusú cukorbetegség

    DOI: The aims of this study were to establish a model of long-term diabetes with sustained medium scale hyperglycemia and characterize the pathological changes detectable after 4months, with particular respect to dependence on the degree of hyperglycemia.

    Methods: Streptozotocin-induced diabetic CFY rats were subjected to four different insulin substitution protocols to achieve different levels of glycemic control Diabetic groups.

    diabetes icd 10 code list hardver eljárások kidolgozását cukorbetegség kezelésére

    Eyes were investigated by ophthalmoscopy, kidney function by urine analysis, and neuropathy by functional tests. Retinal and renal morphological evaluations were performed by histology, immuno-histochemistry and electron microscopy. Discussion: We established a treatment protocol in rats enabling complex investigation of diabetic retinopathy, nephropathy and neuropathy on a long-term period.

    Clearly hyperglycemic dependent parameters of these complications serve as good outcome measures for preclinical trials.

    a cukorbetegség kezelése népi gyógyászat kezelés leve cukorbetegség

    Our results provide a useful basis for diabetes mellitus latest research studies for testing preventative treatments as well as other translational medical research in this field. Keywords: Anterior segment neovascularization; Chronic model; Cold allodynia; Diabetic nephropathy; Diabetic neuropathy; Diabetic retinopathy; Drug development; Insulin implant; Preclinical model; Streptozotocin. Copyright © Elsevier Inc.

    All rights reserved.

    kezelése cukorbetegség fekélyek nonachar cukorbetegség tünetei a gyermekek kezelésében

    Publication types.